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Cancer is not a single disease. Many targeted
drugs only work in a small fraction of patient population,
sometimes across seemingly unrelated cancer types. In order
to achieve the necessary statistical power to cover most of
cancer types, it is necessary to screen candidate compounds
on 300-500 cancer cell lines to:
- Identify cancer indication
- Identify sub-population of highly sensitive
cancer genotypes to generate patient stratification hypothesis
We have collected over 300 cancer cell lines,
as well as our proprietary primary cancer cells which are
backed by detailed patient clinical information and extensive
cDNA microarray data. The Omni Panel will provide the most
comprehensive analysis of lead compound in vitro, and important
resource for predictive biomarker discovery. |