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Anti-angiogenesis is an active area for anti-cancer
drug development. However, many angiogenesis assays are limited
to single time point analysis, and cannot offer longitudal
study of angiogenesis within the same animal.
CrownBio offers two in
vivo angiogensis models:
- Matrigel plug assay
- Window Chamber model
Compared to other assay formats,
Window chamber offers:
- Direct visualization of tumor vascular in vivo
- Real time monitor of vasculature growth on mice
- Longitudal study of drug effect on angiogenesis on the same animal
- Real time monitor of drug release in vivo
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Besides angiogenesis, Window
Chamber technology can also be used in a wide range of applications,
such as drug delivery, cell trafficking and migration. We
will also work with our customers to develop custom solutions
to suit specific research needs.
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