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Non-GLP Toxicity
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DMPK

Appropriate application of in vivo pharmacodynamic study and drug analysis can dramatically speed drug discovery and development. Crownbio offers in vivo and in vitro pharmacokinetic studies of drugs and drug metabolites with fast turnaround times, which will help you make your decisions faster and reducing your total study costs.

In Vivo DMPK Services

Crown bioscience can help you perform all kind of the in vivo PK studies, including:

  • Project/Study planning, Study protocol design and writing
  • in vivo pharmacokinetic studies of drugs and drug metabolites in rats and mice, rabbit, and dog
  • All routes of administration (IP, IV, PO, SC etc.)
  • Continue IV infusion PK for conscious and anesthetized mice, rat and rabbit
  • In vivo Crossover studies for Bioavailability
  • Single, multiple, and cassette dosing
  • Support of toxicity studies To provide blood and tissue samples for pharmacokinetic studies in client laboratories
  • Technical report

In Vitro DMPK Services

 
  • Complete pharmacokinetic analysis
  • Method development and validation
  • Plasma stability
  • In Vivo Exposure
  • Vehicle Screen
  • Protein Binding
  • Mass balance
  • Reporting by using WinNonlin software

>>  Non-GLP Toxicity

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