| Crown Bioscience provides
expertise in producing specific antibodies for therapeutic,
diagnostic and theranostic applications. Our full range of
services includes custom polyclonal and monoclonal antibody
production from antigen expression or peptide synthesis to
antibody purification and labeling. As an industrial leader
specializing in oncology preclinical development services,
Crown Bioscience also provides advanced services capability
in protein engineering and recombinant antibody production.
Antibody based therapies are now recognized as key components
of modern frontline cancer therapies. Crown Bioscience’s
oncology expertise strengthens our design, validation and
development of your therapeutic antibodies for the treatment
of cancer.
QUALITY >> SPEED >> COST
>> IMMUNOGENICITY
Additional Services:
| Stable
cell line development |
Approximately six positive clones
from the first cloning cycle will be selected for the
second cycle. Several cycles of cloning may be required
in order to obtain a true, stable clone. Isolated colonies
will be tested by ELISA and positive selected to expand.
Cells from these positive clones will be frozen in triplicate
as back up. |
| Large
Scale Production |
Produce monoclonal antibodies in milligram
quantities and larger bulk amounts if required. |
| Antibody
Purification |
Purify antibodies by protein A, caprylic
acid or affinity purification. |
| Analytical
assays and Bioassays |
|
| Cell
line Typing |
Isotype monoclonal cell lines. |
| Cell
line Storage |
Store valuable cell lines in liquid
nitrogen if required. |
|
