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In Vitro

Boost oncology drug discovery with XenoBase®, featuring the largest cell line selection and exclusive 3D organoid models. Benefit from OrganoidXplore™ and OmniScreen™ for rapid, in-depth analysis.

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In Vivo

Enhance drug development with our validated in vivo models, in vitro/ex vivo assays, and in silico modeling. Tailored solutions to optimize your candidates.

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Tissue

Experience ISO-certified biobanking quality. Access top biospecimens from a global clinical network, annotated by experts for precise research.

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Biomarkers and Bioanalysis

Leverage our global labs and 150+ scientists for fast, tailored project execution. Benefit from our expertise, cutting-edge tech, and validated workflows for reliable data outcomes.

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Data Science and Bioinformatics

Harness your data and discover biomarkers with our top bioinformatics expertise. Maximize data value and gain critical insights to accelerate drug discovery and elevate projects.

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KRAS

Accelerate innovative cancer treatments with our advanced models and precise drug screening for KRAS mutations, efficiently turning insights into clinical breakthroughs.

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EGFR

Advance translational pharmacology with our diverse pre-clinical models, robust assays, and data science-driven biomarker analysis, multi-omics, and spatial biology.

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Drug Resistance

Our suite integrates preclinical solutions, bioanalytical read-outs, and multi-omics to uncover drug resistance markers and expedite discovery with our unique four-step strategy.

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Patient Tissue

Enhance treatments with our human tumor and mouse models, including xenografts and organoids, for accurate cancer biology representation.

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Bioinformatics

Apply the most appropriate in silico framework to your pharmacology data or historical datasets to elevate your study design and analysis, and to improve your chances of clinical success.

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Biomarker Analysis

Integrate advanced statistics into your drug development projects to gain significant biological insight into your therapeutic candidate, with our expert team of bioinformaticians.

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CRISPR/Cas9

Accelerate your discoveries with our reliable CRISPR solutions. Our global CRISPR licenses cover an integrated drug discovery platform for in vitro and in vivo efficacy studies.

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Genomics

Rely on our experienced genomics services to deliver high quality, interpretable results using highly sensitive PCR-based, real-time PCR, and NGS technologies and advanced data analytics.

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In Vitro High Content Imaging

Gain more insights into tumor growth and disease progression by leveraging our 2D and 3D fluorescence optical imaging.

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Mass Spectrometry-based Proteomics

Next-generation ion mobility mass spectrometry (MS)-based proteomics services available globally to help meet your study needs.

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Ex Vivo Patient Tissue

Gain better insight into the phenotypic response of your therapeutic candidate in organoids and ex vivo patient tissue.

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Spatial Multi-Omics Analysis

Certified CRO services with NanoString GeoMx Digital Spatial Profiling.

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Biomarker Discovery

De-risk your drug development with early identification of candidate biomarkers and utilize our biomarker discovery services to optimize clinical trial design.

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DMPK Services

Rapidly evaluate your molecule’s pharmaceutical and safety properties with our in vivo drug metabolism and pharmacokinetic (DMPK) services to select the most robust drug formulations.

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Efficacy Testing

Explore how the novel HuGEMM™ and HuCELL™ platforms can assess the efficacy of your molecule and accelerate your immuno-oncology drug discovery programs.

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Employ cutting-edge multi-omics methods to obtain accurate and comprehensive data for optimal data-based decisions.

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Pharmacology & Bioanalytical Services

Leverage our suite of structural biology services including, recombinant protein expression and protein crystallography, and target validation services including RNAi.

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Screens

Find the most appropriate screen to accelerate your drug development: discover in vivo screens with MuScreen™ and in vitro cell line screening with OmniScreen™.

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Toxicology

Carry out safety pharmacology studies as standalone assessments or embedded within our overall toxicological profiling to assess cardiovascular, metabolic and renal/urinary systems.

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Our Company

Global CRO in California, USA offering preclinical and translational oncology platforms with high-quality in vivo, in vitro, and ex vivo models.

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We build a sustainable future by supporting employee growth, fostering leadership, and exceeding customer needs. Our values focus on innovation, social responsibility, and community well-being.

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Crown Bioscience Invests in Process Excellence with the Appointment of New Vice President of Global Quality

Pam Shang, CrownBio VP Global QualitySan Diego, Calif – October 8, 2020 — Crown Bioscience today announces the appointment of Pam Shang as vice president for global quality. Mrs. Shang will be instrumental in further enhancing global quality across the company, leveraging her deep expertise in implementing quality systems for pharma and biotechnology clients including in GLP, GMP and other regulated environments.

Building on CrownBio’s existing platforms, Mrs. Shang will be responsible for the strategic direction, enhancement, and growth of CrownBio’s quality systems, underlying organizational processes, and leading the associated change management.

“I am excited to welcome Pam to the leadership team,” said Armin Spura, PhD, chief executive officer of CrownBio. “With her wealth of experience in implementing global quality systems and overseeing GxP initiatives, Pam will ensure that CrownBio puts quality and our customers at the forefront of all CrownBio initiatives”.

Mrs. Shang joins CrownBio from Asahi Kasei America, a Japanese pharmaceutical company, where she was head of global quality and compliance. Pam was responsible for all regulatory matters across diverse areas including quality oversight and control, regulatory compliance, and audit management.

CrownBio has seen consistent quality improvements year-on-year, with associated enhanced client satisfaction. The new strategic initiatives led by Mrs. Shang across global operational platforms will ensure high scientific quality and a continued dedication to enhance standards and performance across the company.

“I’m delighted to bring my expertise to CrownBio”, said Pam Shang. “The quality of our work and compliance to regulatory standards is extremely important, and pivotal for CrownBio’s continued growth. My aim is to ensure that all staff are empowered with proper resources and regulatory knowledge to be successful and accountable, to foster a success-oriented, safe working environment and to ensure the scientific quality of our products and services”.

Mrs. Shang holds a BS in Management Information Systems and a minor in Business from Southern Illinois University. She also completed Master’s Program course requirements in Biotechnology at Harvard University.

Media Enquiries:

Jody Barbeau
Crown Bioscience Inc.
pr@crownbio.com

Upcoming Events

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July 23-24, 2024|Boston, MA | The Westin Boston Seaport District

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