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In Vitro

Boost oncology drug discovery with XenoBase®, featuring the largest cell line selection and exclusive 3D organoid models. Benefit from OrganoidXplore™ and OmniScreen™ for rapid, in-depth analysis.

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In Vivo

Enhance drug development with our validated in vivo models, in vitro/ex vivo assays, and in silico modeling. Tailored solutions to optimize your candidates.

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Tissue

Experience ISO-certified biobanking quality. Access top biospecimens from a global clinical network, annotated by experts for precise research.

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Biomarkers and Bioanalysis

Leverage our global labs and 150+ scientists for fast, tailored project execution. Benefit from our expertise, cutting-edge tech, and validated workflows for reliable data outcomes.

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Data Science and Bioinformatics

Harness your data and discover biomarkers with our top bioinformatics expertise. Maximize data value and gain critical insights to accelerate drug discovery and elevate projects.

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KRAS

Accelerate innovative cancer treatments with our advanced models and precise drug screening for KRAS mutations, efficiently turning insights into clinical breakthroughs.

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EGFR

Advance translational pharmacology with our diverse pre-clinical models, robust assays, and data science-driven biomarker analysis, multi-omics, and spatial biology.

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Drug Resistance

Our suite integrates preclinical solutions, bioanalytical read-outs, and multi-omics to uncover drug resistance markers and expedite discovery with our unique four-step strategy.

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Patient Tissue

Enhance treatments with our human tumor and mouse models, including xenografts and organoids, for accurate cancer biology representation.

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Bioinformatics

Apply the most appropriate in silico framework to your pharmacology data or historical datasets to elevate your study design and analysis, and to improve your chances of clinical success.

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Biomarker Analysis

Integrate advanced statistics into your drug development projects to gain significant biological insight into your therapeutic candidate, with our expert team of bioinformaticians.

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CRISPR/Cas9

Accelerate your discoveries with our reliable CRISPR solutions. Our global CRISPR licenses cover an integrated drug discovery platform for in vitro and in vivo efficacy studies.

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Genomics

Rely on our experienced genomics services to deliver high quality, interpretable results using highly sensitive PCR-based, real-time PCR, and NGS technologies and advanced data analytics.

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In Vitro High Content Imaging

Gain more insights into tumor growth and disease progression by leveraging our 2D and 3D fluorescence optical imaging.

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Mass Spectrometry-based Proteomics

Next-generation ion mobility mass spectrometry (MS)-based proteomics services available globally to help meet your study needs.

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Ex Vivo Patient Tissue

Gain better insight into the phenotypic response of your therapeutic candidate in organoids and ex vivo patient tissue.

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Spatial Multi-Omics Analysis

Certified CRO services with NanoString GeoMx Digital Spatial Profiling.

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Biomarker Discovery

De-risk your drug development with early identification of candidate biomarkers and utilize our biomarker discovery services to optimize clinical trial design.

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DMPK Services

Rapidly evaluate your molecule’s pharmaceutical and safety properties with our in vivo drug metabolism and pharmacokinetic (DMPK) services to select the most robust drug formulations.

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Efficacy Testing

Explore how the novel HuGEMM™ and HuCELL™ platforms can assess the efficacy of your molecule and accelerate your immuno-oncology drug discovery programs.

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Laboratory Services

Employ cutting-edge multi-omics methods to obtain accurate and comprehensive data for optimal data-based decisions.

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Pharmacology & Bioanalytical Services

Leverage our suite of structural biology services including, recombinant protein expression and protein crystallography, and target validation services including RNAi.

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Screens

Find the most appropriate screen to accelerate your drug development: discover in vivo screens with MuScreen™ and in vitro cell line screening with OmniScreen™.

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Toxicology

Carry out safety pharmacology studies as standalone assessments or embedded within our overall toxicological profiling to assess cardiovascular, metabolic and renal/urinary systems.

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Our Company

Global CRO in California, USA offering preclinical and translational oncology platforms with high-quality in vivo, in vitro, and ex vivo models.

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Our Purpose

Learn more about the impact we make through our scientific talent, high-quality standards, and innovation.

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Our Responsibility

We build a sustainable future by supporting employee growth, fostering leadership, and exceeding customer needs. Our values focus on innovation, social responsibility, and community well-being.

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Meet Our Leadership Team

We build a sustainable future by fostering leadership, employee growth, and exceeding customer needs with innovation and social responsibility.

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Scientific Advisory Board

Our Scientific Advisory Board of experts shapes our strategy and ensures top scientific standards in research and development.

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News & Events

Stay updated with Crown Bioscience's latest news, achievements, and announcements. Check our schedule for upcoming events and plan your visit.

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Career Opportunities

Join us for a fast-paced career addressing life science needs with innovative technologies. Thrive in a respectful, growth-focused environment.

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Scientific Publications

Access our latest scientific research and peer-reviewed articles. Discover cutting-edge findings and insights driving innovation and excellence in bioscience.

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Resources

Discover valuable insights and curated materials to support your R&D efforts. Explore the latest trends, innovations, and expertly curated content in bioscience.

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Blogs

Explore our blogs for the latest insights, research breakthroughs, and industry trends. Stay educated with expert perspectives and in-depth articles driving innovation in bioscience.

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Our Company

Headquartered in California, US, Crown Bioscience is a global contract research organization (CRO) providing discovery, preclinical and translational platforms and services to advance oncology and immuno-oncology.

We are known for our high-quality and expansive in vivo, in vitro, and ex vivo preclinical models, and partner with our clients to quantify the efficacy and pharmacological profile of their drug candidate(s) before they move into the clinic. We aim to deliver superior drug candidates to ensure that patients get the right treatment at the right time.

  1. 2006

    Crown Bioscience Inc. founded

  2. 2007
    Oncology Platform Established
  3. 2008
    Biologics platform established

    New R&D Centre founded in Taicang, China

  4. 2009

    Crown Bioscience US R&D site founded

  5. 2013

    Acquisition of PRECOS Ltd. (Now Crown Bioscience UK)

  6. 2013
    Bioluminescence Imaging platform established
  7. 2014

    Crown BioScience Taiwan founded

  8. 2015

    Expansion of Western PDX Models

  9. 2015

    Expansion of Western PDX Models

  10. 2017

    Acquisition of Molecular Response (Now Crown Bioscience San Diego, US)

  11. 2017
    Inflammation Platform Established
  12. 2017

    Expansion of UK & US Oncology Facilities

  13. 2018

    Expansion of Bioinformatics Facilities, Suzhou, China

  14. 2018

    Acquisition by JSR Corporation

  15. 2019
    Organoid Platform Established
  16. 2020

    Expansion of China Oncology Facilities in Zhongshan

  17. 2020

    Crown Bioscience Netherlands organoid center founded

  18. 2021

    Acquisition of OcellO B.V. Expansion of in vitro capability

  19. 2022

    Crown Bioscience & MBL Joint Venture Established in Japan

  20. 2023

    Crown Bioscience Singapore founded

  21. 2023

    Acquisition of Indivumed Services

 

Our Brand

 


About JSR Life Sciences

JSR Life SciencesCrown Bioscience is a division of JSR Life Sciences, part of the multinational JSR Corporation.

JSR Life Sciences provides specialized technology, products, materials, and services to biopharmaceutical companies and life science researchers.

Through the service offerings of our affiliates, including Crown Bioscience, JSR has created a framework that provides a fully integrated drug development process, from discovery through commercial production, that accelerates development timelines and can increase clinical success rates.

Crown Bioscience is a global contract research organization (CRO) providing discovery, preclinical, and translational platforms to advance oncology and immuno-oncology.

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indivumed-logo

Indivumed Services is a global contract research organization (CRO) that offers an industry-leading oncology biobank and a range of service platforms to advance oncology and immuno-oncology drug discovery and development.

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MBL implements biomarker discovery for companion diagnostics, and the development and manufacturing of in vitro diagnostics (IVDS) for immunological and genetic testing.

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KBI Biopharma provides deep analytical services, process development, and GMP manufacturing for clinical trials and commercialization of biopharmaceuticals.

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