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HuGEMM™

HuGEMM™ Models represent a pivotal advancement in immuno-oncology research, offering a revolutionary approach to testing human-specific therapeutics within a murine immune system context. As cancer remains a formidable challenge globally, necessitating innovative solutions, HuGEMM™ provides a unique avenue for understanding and combating this disease. By harnessing the power of humanized models, researchers gain unprecedented insights into the interplay between therapeutic agents and the complex immune response, driving forward the development of novel treatments. With CrownBio's HuGEMM™ platform, embark on a transformative journey towards precision oncology, where cutting-edge science meets the demands of real-world clinical challenges.

MODEL NUMBER TYPE MOUSE STRAIN # per page
huCD137 Single Knock-In C57BL/6 CLICK TO VIEW
huCD3E Transgenic BALB/C CLICK TO VIEW
huCD40 Single Knock-In C57BL/6 CLICK TO VIEW
huCTLA-4 Single Knock-In C57BL/6 CLICK TO VIEW
huLAG3 Single Knock-In C57BL/6 CLICK TO VIEW
huOX40 Single Knock-In C57BL/6 CLICK TO VIEW
huPD-1 Single Knock-In C57BL/6 CLICK TO VIEW
huPD-1/CTLA-4 Double Knock-In C57BL/6 CLICK TO VIEW
huPD-1/huPD-L1 Double Knock-In C57BL/6 CLICK TO VIEW
huPD-1/LAG3 Double Knock-In C57BL/6 CLICK TO VIEW
huPD-1/OX40 Double Knock-In C57BL/6 CLICK TO VIEW
huPD-L1 Single Knock-In C57BL/6 CLICK TO VIEW
huPD-L1/LAG3 Double Knock-In C57BL/6 CLICK TO VIEW

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