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Adrenal Gland Cancer PDX Models

Suitable preclinical models such as patient-derived xenografts (PDX) are needed to evaluate drugs specifically targeting adrenal gland cancer. PDX models are known to be the most predictive preclinical model and provide the most accurate approach to evaluating an agents efficacy prior to entering the clinic. The Crown Bioscience adrenal gland PDX collection consists of several models, including models from both North American and Asian descent. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. Crown Bioscience's HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.

MODEL NUMBER CANCER TYPE CANCER SUBTYPE DESCRIPTION # per page
AD0344 Adrenal Gland Cancer NA Small cell carcinoma of left adrenal gland, infiltrating into soft tissue of left kidney. No malignant cell adjacent to urethral stump. IHC results: Syn(+), Chr-A(+), CK(+), NSE(+), Vim(-). CLICK TO VIEW
AD0484 Adrenal Gland Cancer NA NA for clinical diagnosis info. CLICK TO VIEW
AD10272 Adrenal Gland Cancer NA Adrenal cortical carcinoma CLICK TO VIEW

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