<img height="1" width="1" src="https://www.facebook.com/tr?id=1582471781774081&amp;ev=PageView &amp;noscript=1">

Gallbladder Cancer PDX Models

Suitable preclinical models such as patient-derived xenografts (PDX) are needed to evaluate therapies specifically targeting gallbladder cancer. PDX models are known to be the most predictive preclinical model and provide the most accurate approach to evaluating an agent’s efficacy prior to entering the clinic. The Crown Bioscience gallbladder cancer PDX collection consists of several models, including models from both North American and Asian descent. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. Crown Bioscience 's HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.

MODEL NUMBER CANCER TYPE CANCER SUBTYPE DESCRIPTION # per page
GL0440 Gallbladder Cancer ADC Adenocarcinoma of gallbladder, invade surrounding soft tissues. Metastatic tumor foci were observed in liver. No visible malignant cells adjacent to neck of gallbladder. CLICK TO VIEW
GL0608 Gallbladder Cancer ADC Adenocarcinoma of gallbladder, invade surrounding soft tissues. Regional LN: the eighth group LN (1/1). CLICK TO VIEW
GL0720 Gallbladder Cancer ADC Adenocarcinoma from connective tissue, poorly differentiated. Based on IHC results, consider tumor from biliary track . IHC results: CK7(+++), CK20(-), CK(++), TTF-I(-), ER(-), PR(-), CerbB-2(++), Ki-67(80%), p53 (+++), TG (-). CLICK TO VIEW
GL11310 Gallbladder Cancer NA Klatskin Tumor CLICK TO VIEW
GL11319 Gallbladder Cancer NA NA CLICK TO VIEW
GL1208 Gallbladder Cancer ADC Adenosquamous carcinoma of gallbladder, invasive through cholecystic wall and biliary ducts. CLICK TO VIEW
GL1418 Gallbladder Cancer ADC Adenocarcinoma of gallbladder with hepatatic metastases, moderately differentiated. CLICK TO VIEW
GL3014 Gallbladder Cancer ADC Metastatic cholecystic adenocarcinoma to hepatic tissue, moderately differentiated. The tumor forms glandular, cribriform structures and has an infiltrative growth pattern. CLICK TO VIEW
GL3379 Gallbladder Cancer ADC Common bile duct: moderately differentiated adenocarcinoma. The tumor infiltrated gall bladder wall. One of one lymph node involved by malignant carcinoma (1/1). CLICK TO VIEW
GL6899 Gallbladder Cancer ADS Adenosquamous carcinoma from juncture of liver and gallblader (moderately to poorly differentiated adenocarcinoma, moderately differentiated squamous cell carcinoma) with necrosis. No lymph nodes involved by metastatic carcinoma (0/9). CLICK TO VIEW

Sorry, no posts matched your criteria.

Create Account to View All Model Data

Already Registered? Login