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Patient-Derived Xenograft Models of Pancreatic Cancer

Patient-derived xenograft (PDX) models provide a predictive preclinical model for the evaluation of an agent’s efficacy prior to entering the clinic. The Crown Bioscience pancreatic collection contains over 100 models, including models of both North American and Asian descent. More

Benefits of Crown Bioscience's Pancreatic Cancer PDX Models

Our pancreatic cancer patient-derived xenograft models offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, Patient derived xenografts reflect the heterogeneity and diversity of the human patient population. PDX will give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. Crown Bioscience's HuPrime® Pancreatic cancer PDX model collection is well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.

MODEL NUMBER CANCER TYPE CANCER SUBTYPE DESCRIPTION # per page
PA0226 Pancreatic Cancer Adenocarcinoma N/A CLICK TO VIEW
PA0372 Pancreatic Cancer ADC Adenocarcinoma of right axillary region, poorly differentiated. Regional LN: right axillary LN (20/22). CLICK TO VIEW
PA0527 Pancreatic Cancer ADC Adenocarcinoma of head of pancreas. No malignant cells adjacent to both stump, duodenal wall and common bile duct. Regional LN: the eighth group LN (0/1), the twelfth group (0/1), posterior head of pancreatic LN (1/1). Chronic cholecystitis. CLICK TO VIEW
PA0573 Pancreatic Cancer NA NA for clinical diagnosis info. CLICK TO VIEW
PA0692 Pancreatic Cancer ADC Moderately to poorly differentiated adenocarcinoma CLICK TO VIEW
PA0787 Pancreatic Cancer ADC Metastatic adenocarcinoma in LN, consider originate from pancreas. IHC results: CK(++), CK7(++), CK18(+), CK19(++), CK20(-), CK34(++), CEA(+), CA125(+), CA19-9(+), Ki67(++), AFP(-), Hepatocyte(+/-), Syn(-), Vimentin(-), LCA(+). CLICK TO VIEW
PA0968 Pancreatic Cancer ADC NA for clinical diagnosis info. CLICK TO VIEW
PA1168 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma of head of pancreas, moderately differentiated. Chronic cholecystitis. CLICK TO VIEW
PA1170 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma of head of pancreas, moderately differentiated. CLICK TO VIEW
PA1178 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma with part of mucinous adenocarcinoma of head of pancreas, moderately differentiated.tumor mass: 4cm x 3cm x 2cm, invaded duodenal mucosa. Regional LN: parapancreatic LN (4/6). Chronic cholecystitis. CLICK TO VIEW
PA1189 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma of head of pancreas, moderately differentiated, tumor mass: 2cm x 1cm x 1cm, invaded choledochal wall and muscular layer of duodenum. Regional LN: parapancreatic LN: (0/8). Chronic cholecystitis. CLICK TO VIEW
PA1194 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma of head of pancreas, moderately-poorly differentiated, tumor mass: 3cm x 3cm x 3cm, invaded nerve tissue, adipose tissue around pancreas. Regional LN: parapancreatic LN: (1/5). Chronic cholecystitis. CLICK TO VIEW
PA1198 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma of head of pancreas, moderately differentiated. Regional LN: parapancreatic LN (0/3), LN of hepatoduodenal ligament (0/9). Chronic cholecystitis. CLICK TO VIEW
PA1214 Pancreatic Cancer ADC Adenocarcinoma of head of pancreas, moderately differentiated, infiltrating through duodenal wall. Regional LN: paragastric LN (0/4). Chronic cholecystitis. CLICK TO VIEW
PA1221 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma of head of pancreas, moderately differentiated, infiltrating duodenal muscularis mucosa. Regional LN: parapancreatic LN (1/2). Chronic cholecystitis. CLICK TO VIEW
PA1222 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma of head of pancreas, moderately differentiated. Regional LN: parapancreatic LN (2/3), LN of margo inferior pancreas (0/2). Chronic cholecystitis. CLICK TO VIEW
PA1226 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma of head of pancreas, moderately differentiated. Regional LN: parapancreatic LN (2/3), LN of margo inferior pancreas (0/2). Chronic cholecystitis. CLICK TO VIEW
PA1229 Pancreatic Cancer ADC Adenocarcinoma of head of pancreas, moderately-poorly differentiated. Intraductal papillary mucinous neoplasms of body of pancreas. CLICK TO VIEW
PA1233 Pancreatic Cancer Ductal adenocarcinoma 1.Ductal adenocarcinoma of body and tail of pancreas, moderately differentiated, tumor mass: 3 x 2 x 2cm. Regional LN: parapancreatic LN (0/3). 2.Chronic splenic congestion. CLICK TO VIEW
PA1252 Pancreatic Cancer Ductal adenocarcinoma Ductal adenocarcinoma of head of pancreas, moderately differentiated, tumor mass: 2.5 x 2 x 2cm. Regional LN: parapancreatic-bile duct LN (1/20). CLICK TO VIEW
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