JC

Model Information:

JC is a cell line of the malignant neoplasm of the mouse mammary gland. It is an epithelial-like cell line established from a spontaneous primary mammary adenocarcinoma along the milk line⁽¹⁾. The model offers a suitable platform for the efficacy and PD evaluation of single and combination I/O agent therapies. At CrownBio, the JC model is offered as a subcutaneous model in the flank.

Summary
Cancer Type	Breast Cancer
Mouse Strain	BALB/c
TMA	TMA-CP-SY-008

Response to Immune Checkpoint Inhibitors

Additional Characteristics

⁽¹⁾ Characterization of a new spontaneously developed murine mammary adenocarcinoma in syngeneic BALB/c hosts. In Vitro Cell. Dev. Biol. 25: 621-626, 1989.