mBN6091

Model Information:

This strain carries a conditional mutant Kras (KrasLSL-G12D/WT) and a conditional knock out of PTEN (PTENflox/flox). G12D mutant Kras was activated and PTEN was knocked out upon administrating the adeno-cre virus, which resulted in a tumor in the brain approximately 6 months later.

Summary
Cancer Type	Brain Cancer
Mutations	KRAS (G12D); PtenFlox/Flox
Biopsy Site	Brain
Pathology QC	Glioblastoma (P1)
Mouse Strain	C57BL/6

Growth Characteristics

Additional Characteristics