mPA6114

Model Information:

This strain carries a conditional mutant Kras (KrasLSL-G12D/WT), a constitutive deletion of Trp53 (p53KO/KO) and a Cre driven by the promoter of Pdx1 gene. The mouse developed a severe pancreatic tumor and was near death at the age of 8 weeks.

Summary
Cancer Type	Pancreatic Cancer
Mutations	KRAS (G12D); P53-/-;Pdx-1 cre
Biopsy Site	Pancreases
Pathology QC	Moderately differentiated adenocarcinoma (P5, Pa)
Mouse Strain	C57BL/6

Growth Characteristics

Additional Characteristics