eBook: A New Dimension to Drug Discovery

Crown Bioscience has merged our OrganoidBase™ resource with High Content Services (HCS), to provide you with more data, deeper insights, and better results in less time.

In this eBook you will learn:

About OrganoidBase™:

This easy-to-use resource features characterization data for our growing biobank of more than 200 PDXO models, representing multiple different cancers types, matched to patient and PDX features. It is being expanded to also include data from Hubrecht Organoid Technology (HUB) patient-derived tumor organoids and corresponding healthy tissue organoids.

About High Content Services:

Crown Bioscience's High Content Services can significantly enhance your research by providing insights at a microscopic level and beyond, adding value in several key ways:

• High-Content Imaging (HCI): HCI is a powerful method that merges automated microscopy and fluorescent detection techniques, providing you with a deeper understanding of the interactions occurring within and between various cell populations. This technology is not just about capturing high-quality images, it's about the analysis of intricate cellular behaviors in a visual and quantifiable manner. It opens up new dimensions of cellular interaction and tissue biology, enabling researchers to examine how cells behave in their natural environments, monitor their responses, and study potential therapeutic effects.
  
  
• High-Content Screening (HCS): Simultaneously screen millions of compounds in complex cellular model systems for more predictive results
  
  
• High-Content Analysis (HCA): Apply multiparameter algorithms to HCI data, to monitor multiple features within one microenvironment

Crown’s HCS, when coupled with OrganoidBase™, can deliver clinically relevant, high-throughput phenotypic analyses at subcellular resolution across several phases of the drug discovery pipeline, from hit identification to lead optimization.