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Boost oncology drug discovery with XenoBase®, featuring the largest cell line selection and exclusive 3D organoid models. Benefit from OrganoidXplore™ and OmniScreen™ for rapid, in-depth analysis.
Enhance drug development with our validated in vivo models, in vitro/ex vivo assays, and in silico modeling. Tailored solutions to optimize your candidates.
Experience ISO-certified biobanking quality. Access top biospecimens from a global clinical network, annotated by experts for precise research.
Leverage our global labs and 150+ scientists for fast, tailored project execution. Benefit from our expertise, cutting-edge tech, and validated workflows for reliable data outcomes.
Harness your data and discover biomarkers with our top bioinformatics expertise. Maximize data value and gain critical insights to accelerate drug discovery and elevate projects.
Accelerate innovative cancer treatments with our advanced models and precise drug screening for KRAS mutations, efficiently turning insights into clinical breakthroughs.
Advance translational pharmacology with our diverse pre-clinical models, robust assays, and data science-driven biomarker analysis, multi-omics, and spatial biology.
Our suite integrates preclinical solutions, bioanalytical read-outs, and multi-omics to uncover drug resistance markers and expedite discovery with our unique four-step strategy.
Enhance treatments with our human tumor and mouse models, including xenografts and organoids, for accurate cancer biology representation.
Apply the most appropriate in silico framework to your pharmacology data or historical datasets to elevate your study design and analysis, and to improve your chances of clinical success.
Integrate advanced statistics into your drug development projects to gain significant biological insight into your therapeutic candidate, with our expert team of bioinformaticians.
Accelerate your discoveries with our reliable CRISPR solutions. Our global CRISPR licenses cover an integrated drug discovery platform for in vitro and in vivo efficacy studies.
Rely on our experienced genomics services to deliver high quality, interpretable results using highly sensitive PCR-based, real-time PCR, and NGS technologies and advanced data analytics.
Gain more insights into tumor growth and disease progression by leveraging our 2D and 3D fluorescence optical imaging.
Next-generation ion mobility mass spectrometry (MS)-based proteomics services available globally to help meet your study needs.
Gain better insight into the phenotypic response of your therapeutic candidate in organoids and ex vivo patient tissue.
Certified CRO services with NanoString GeoMx Digital Spatial Profiling.
De-risk your drug development with early identification of candidate biomarkers and utilize our biomarker discovery services to optimize clinical trial design.
Rapidly evaluate your molecule’s pharmaceutical and safety properties with our in vivo drug metabolism and pharmacokinetic (DMPK) services to select the most robust drug formulations.
Explore how the novel HuGEMM™ and HuCELL™ platforms can assess the efficacy of your molecule and accelerate your immuno-oncology drug discovery programs.
Employ cutting-edge multi-omics methods to obtain accurate and comprehensive data for optimal data-based decisions.
Leverage our suite of structural biology services including, recombinant protein expression and protein crystallography, and target validation services including RNAi.
Find the most appropriate screen to accelerate your drug development: discover in vivo screens with MuScreen™ and in vitro cell line screening with OmniScreen™.
Carry out safety pharmacology studies as standalone assessments or embedded within our overall toxicological profiling to assess cardiovascular, metabolic and renal/urinary systems.
Global CRO in California, USA offering preclinical and translational oncology platforms with high-quality in vivo, in vitro, and ex vivo models.
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The immune system plays a vital role in defending the body against disease, and many drugs are designed to target the immune system to treat conditions such as cancer, autoimmune disorders, and infectious diseases. By understanding and monitoring the immune systems response to a drug, researchers can potentially develop more effective and safer drugs to improve patient outcomes.
Evaluate the safety of a drug candidate. Many drug candidates trigger an immune response that can cause adverse reactions, such as allergies, hypersensitivity, cytokine storm, or autoimmune disorders. By monitoring the immune response of a drug candidate, researchers can identify potential safety issues early in the development process, allowing them to modify their molecule accordingly.
Determine the efficacy of a drug candidate. Many drug candidates that target the immune system have off-target effects or trigger an incomplete immune response. By monitoring the immune response, researchers can evaluate whether the drug candidate is effectively modulating the immune response and fighting the disease.
Establish preferred patient populations. Immune responses are complex and can be influenced by various factors, including genetics, environmental factors, and comorbidities. Monitoring the immune response allows researchers to identify patient subgroups that may respond differently to the drug candidate and adjust the molecule's dose, regimen, or formulation to improve its effectiveness.
Identify potential biomarkers of drug response. Biomarkers can be used to predict whether a drug candidate will be effective in treating a particular disease or patient population. Researchers can identify potential biomarkers that can be used to predict which patients will respond to the drug and optimize patient selection by monitoring the immune response of their drug candidate
We offer a wide collection of immune monitoring assays, including some unique services. Rely on our immunological expertise, broad capabilities, flexibility to customize assays to your special needs, quick turnaround, and cost-efficient services to accelerate your drug development:
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